T. W. Synold : rechercher sur Z-Library

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1

Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia

William R. Crom, Siebold S.N. de Graaf, Timothy Synold, Donald R.A. Uges, Henk Bloemhof, Gaston Rivera, Michael L. Christensen, Hazem Mahmoud, William E. Evans

Journal:

The Journal of Pediatrics

Année:

1994

Langue:

english

Fichier:

PDF, 600 KB

english, 1994

2

A phase I trial of mushroom powder in patients with biochemically recurrent prostate cancer: Roles of cytokines and myeloid-derived suppressor cells for Agaricus bisporus -induced prostate-specific antigen responses

Twardowski, Przemyslaw, Kanaya, Noriko, Frankel, Paul, Synold, Timothy, Ruel, Christopher, Pal, Sumanta K., Junqueira, Maribel, Prajapati, Manisha, Moore, Tina, Tryon, Pamela, Chen, Shiuan

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 255 KB

english, 2015

3

Prevention of early renal disease, dyslipidaemia and lipid peroxidation in STZ-diabetic rats by LR-9 and LR-74, novel AGE inhibitors

James Lester Figarola, Steven Scott, Sofia Loera, Bixin Xi, Timothy Synold, Lawrence Weiss, Dr Samuel Rahbar

Journal:

Diabetes/Metabolism Research and Reviews

Année:

2005

Langue:

english

Fichier:

PDF, 372 KB

english, 2005

4

A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168)

Jennifer J. Knox, Sharlene Gill, Timothy W. Synold, James J. Biagi, Pierre Major, Ron Feld, Christine Cripps, Nancy Wainman, Elizabeth Eisenhauer, Lesley Seymour

Journal:

Investigational New Drugs

Année:

2008

Langue:

english

Fichier:

PDF, 338 KB

english, 2008

5

A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial

Christopher W. Lee, Karl Bélanger, Sanjay C. Rao, Teresa M. Petrella, Richard G. Tozer, Lori Wood, Kerry J. Savage, Elizabeth A. Eisenhauer, Timothy W. Synold, Nancy Wainman, Lesley Seymour

Journal:

Investigational New Drugs

Année:

2008

Langue:

english

Fichier:

PDF, 145 KB

english, 2008

6

Neural Stem Cell-Mediated Delivery of Irinotecan-Activating Carboxylesterases to Glioma: Implications for Clinical Use

Metz, M. Z., Gutova, M., Lacey, S. F., Abramyants, Y., Vo, T., Gilchrist, M., Tirughana, R., Ghoda, L. Y., Barish, M. E., Brown, C. E., Najbauer, J., Potter, P. M., Portnow, J., Synold, T. W., Aboody,

Journal:

Stem Cells Translational Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2013

7

An Exploratory Study of Color Discrimination of Children

Synolds, D. L., Pronko, N. H.

Journal:

The Pedagogical Seminary and Journal of Genetic Psychology

Année:

1949

Langue:

english

Fichier:

PDF, 303 KB

english, 1949

8

An Experiment in Pursuit of “Color-Blindness”

Pronko, N. H., Bowles, J. W., Snyder, F. W., Synolds, D. L.

Journal:

The Pedagogical Seminary and Journal of Genetic Psychology

Année:

1949

Langue:

english

Fichier:

PDF, 886 KB

english, 1949

9

Inhibition of MDR1 Overcomes Resistance to Brentuximab Vedotin in Hodgkin Lymphoma

Chen, Robert, Herrera, Alex F., Hou, Jessie, Chen, Lu, Wu, Jun, Guo, Yuming, Synold, Timothy W., Ngo, Vu N., Puverel, Sandrine, Mei, Matthew, Popplewell, Leslie, Yi, Shuhua, Song, Joo Y., Tao, Shu, Wu

Journal:

Clinical Cancer Research

Année:

2019

Langue:

english

Fichier:

PDF, 1018 KB

english, 2019

10

CCI-779 in metastatic melanoma : A Phase II trial of the California Cancer Consortium

Kim Margolin, Jeffrey Longmate, Tracey Baratta, Tim Synold, Scott Christensen, Jeffrey Weber, Thomas Gajewski, Ian Quirt, James H. Doroshow

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 67 KB

english, 2005

11

Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase

Qiang Gao, R. Steven Esworthy, Byung-Wook Kim, Timothy W. Synold, David D. Smith, Fong-Fong Chu

Journal:

Inflammatory Bowel Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 3.20 MB

english, 2010

12

Quantification of chemotherapeutic target gene mRNA expression in human breast cancer biopsies: Comparison of real-time reverse transcription-PCR vs. Relative quantification reverse transcription-PCR utilizing DNA sequencer analysis of PCR products

Agnes Juhasz, Paul Frankel, Catherine Cheng, Hector Rivera, Reena Vishwanath, Alice Chiu, Kim Margolin, Yun Yen, Edward M. Newman, Tim Synold, Sharon Wilczynski, Heinz-Josef Lenz, David Gandara, Kathy

Journal:

Journal of Clinical Laboratory Analysis

Année:

2003

Langue:

english

Fichier:

PDF, 196 KB

english, 2003

13

Simple and sensitive method for the quantitative analysis of lometrexol in plasma using high-performance liquid chromatography with electrochemical detection

Timothy W. Synold, Bixin Xi, Edward M. Newman, Franco M. Muggia, James H. Doroshow

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1996

Langue:

english

Fichier:

PDF, 374 KB

english, 1996

14

Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors

Peter J. Houghton, Pamela J. Cheshire, Leann Myers, Clinton F. Stewart, Timothy W. Synold, Janet A. Houghton

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1992

15

Phase I pharmacodynamic study of time and sequence dependency of hydroxyurea in combination with gemcitabine: a California Cancer Consortium Trial

Yun Yen, Warren Chow, Lucille Leong, Kim Margolin, Robert Morgan, James Raschko, Stephen Shibata, George Somlo, Przemyslaw Twardowski, Paul Frankel, Jeff Longmate, Timothy Synold, Edward M. Newman, He

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 196 KB

english, 2002

16

Phase I trial of continuous infusion 5-aza-2′-deoxycytidine

A. Aparicio, C. A. Eads, L. A. Leong, P. W. Laird, E. M. Newman, T. W. Synold, S. D. Baker, M. Zhao, J. S. Weber

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 307 KB

english, 2003

17

Feasibility and pharmacokinetic study of infusional dexrazoxane and dose-intensive doxorubicin administered concurrently over 96

Warren A. Chow, Timothy W. Synold, Merry L. Tetef, Jeffrey Longmate, Paul Frankel, Joyce Lawrence, Zaid Al-Khadimi, Lucille Leong, Dean Lim, Kim Margolin, Robert J. Morgan, James Raschko, Stephen Shib

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 216 KB

english, 2004

18

Phase II trial of carboplatin and infusional cyclosporine in platinum-resistant recurrent ovarian cancer

Robert J. Morgan, Timothy W. Synold, David Gandara, Franco Muggia, Sidney Scudder, Eddie Reed, Kim Margolin, James Raschko, Lucille Leong, Stephen Shibata, Merry Tetef, Steven Vasilev, Kathryn McGonig

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 215 KB

english, 2004

19

A phase I study of oxaliplatin in combination with gemcitabine: correlation of clinical outcome with gene expression

Stephen Shibata, Warren Chow, Paul Frankel, Agnes Juhasz, Lucille Leong, Dean Lim, Kim Margolin, Robert Morgan, Edward Newman, George Somlo, Yun Yen, Timothy Synold, David Gandara, Heinz-Josef Lenz, J

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 386 KB

english, 2007

20

Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU)

Jan H. Beumer, Robert A. Parise, Edward M. Newman, James H. Doroshow, Timothy W. Synold, Heinz-Josef Lenz, Merrill J. Egorin

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 321 KB

english, 2008

21

Phase I trial of GTI-2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study

Stephen I. Shibata, James H. Doroshow, Paul Frankel, Timothy W. Synold, Yun Yen, David R. Gandara, Heinz-Josef Lenz, Warren A. Chow, Lucille A. Leong, Dean Lim, Kim A. Margolin, Robert J. Morgan, Geor

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 310 KB

english, 2009

22

Plasma and cerebrospinal fluid pharmacokinetics of topotecan in a phase I trial of topotecan, tamoxifen, and carboplatin, in the treatment of recurrent or refractory brain or spinal cord tumors

Robert J. Morgan, Timothy Synold, Adam Mamelak, Dean Lim, Zaid Al-Kadhimi, Przemyslaw Twardowski, Lucille Leong, Warren Chow, Kim Margolin, Stephen Shibata, George Somlo, Yun Yen, Paul Frankel, James

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 258 KB

english, 2010

23

A phase I study of bortezomib and temozolomide in patients with advanced solid tumors

J. Portnow, P. Frankel, S. Koehler, P. Twardowski, S. Shibata, C. Martel, R. Morgan, M. Cristea, W. Chow, D. Lim, V. Chung, K. Reckamp, L. Leong, T. W. Synold

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 384 KB

english, 2012

24

A phase I and pharmacokinetic study of oral 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in the treatment of advanced-stage solid cancers: a California Cancer Consortium Study

Joseph Chao, Timothy W. Synold, Robert J. Morgan, Charles Kunos, Jeff Longmate, Heinz-Josef Lenz, Dean Lim, Stephen Shibata, Vincent Chung, Ronald G. Stoller, Chandra P. Belani, David R. Gandara, Mark

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 259 KB

english, 2012

25

A phase I study of carboplatin and etoposide administered in conjunction with dipyridamole, prochlorperazine and cyclosporine A

James W. Raschko, Timothy W. Synold, Warren Chow, Paul Coluzzi, Victor Hamasaki, Lucille A. Leong, Kim A. Margolin, Robert J. Morgan, Stephen I. Shibata, George Somlo, Merry L. Tetef, Yun Yen, Anna te

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 124 KB

english, 2000

26

Continuous infusion prochlorperazine: pharmacokinetics, antiemetic efficacy, and feasibility of high-dose therapy

Robert J. Morgan Jr, Timothy Synold, Brian I. Carr, James H. Doroshow, Eleanor P. Womack, Stephen Shibata, George Somlo, James Raschko, Lucille Leong, Mark McNamara, Warren Chow, Merry Tetef, Kim Marg

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 145 KB

english, 2001

27

Weekly lometrexol with daily oral folic acid is appropriate for phase II evaluation

John D. Roberts, Elizabeth A. Poplin, Mary Beth Tombes, Brenda Kyle, Darcy V. Spicer, Steven Grant, Timothy Synold, Richard Moran

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 116 KB

english, 2000

28

High-dose toremifene as a cisplatin modulator in metastatic non-small cell lung cancer: targeted plasma levels are achievable clinically

Primo N. Lara Jr., David R. Gandara, Gregory T. Wurz, Derick Lau, Margaret Uhrich, Corinne Turrell, James Raschko, Martin J. Edelman, Timothy Synold, James Doroshow, Franco Muggia, Edith A. Perez, Mik

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 136 KB

english, 1998

29

Oblimersen and α-interferon in metastatic renal cancer: a phase II study of the California Cancer Consortium

Kim Margolin, Timothy W. Synold, Primo Lara, Paul Frankel, Simon F. Lacey, David I. Quinn, Tracey Baratta, Janice P. Dutcher, Bixin Xi, Don J. Diamond, David R. Gandara

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2007

Langue:

english

Fichier:

PDF, 277 KB

english, 2007

30

Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck

Patricia A. Tang, Lillian L. Siu, Eric X. Chen, Sebastien J. Hotte, Stephen Chia, James K. Schwarz, Gregory R. Pond, Caitlin Johnson, A. Dimitrios Colevas, Timothy W. Synold, Lakshmi S. Vasist, Eric W

Journal:

Investigational New Drugs

Année:

2008

Langue:

english

Fichier:

PDF, 262 KB

english, 2008

31

The Effect of Height on Paclitaxel Nerve Damage

Harry Openshaw, Karen Beamon, Jeffrey Longmate, Timothy Synold, Neal E. Slatkin, George Somlo

Journal:

Journal of Neuro-Oncology

Année:

2005

Langue:

english

Fichier:

PDF, 254 KB

english, 2005

32

Phase II trial of carboplatin and infusional cyclosporine with alpha-interferon in recurrent ovarian cancer: a California Cancer Consortium Trial

R.J. MORGAN Jr, T.W. SYNOLD, D. GANDARA, F. MUGGIA, S. SCUDDER, E. REED, K. MARGOLIN, J. RASCHKO, L. LEONG, S. SHIBATA, M. TETEF, S. VASILEV, K. McGONIGLE, J. LONGMATE, Y. YEN, W. CHOW, G. SOMLO, M. C

Journal:

International Journal of Gynecological Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 103 KB

english, 2007

33

10.1038/87912

Synold, Timothy W., Dussault, Isabelle, Forman, Barry Marc

Journal:

Nature Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 634 KB

english, 2001

34

A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia

Kirschbaum, M H, Synold, T, Stein, A S, Tuscano, J, Zain, J M, Popplewell, L, Karanes, C, O'Donnell, M R, Pulone, B, Rincon, A

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 213 KB

english, 2011

35

Neural network (NN) and linear regression limited sampling models (LSM) for etoposide (E) auc determinations.

Lum, B.L., Synold, T.W., Lane, K., Chamick, S.B., Sikic, B.I.

Journal:

Clinical Pharmacology & Therapeutics

Année:

1996

Langue:

english

Fichier:

PDF, 121 KB

english, 1996

36

Renoprotective and Lipid-Lowering Effects of LR Compounds, Novel Advanced Glycation End Product Inhibitors, in Streptozotocin-Induced Diabetic Rats

JAMES LESTER FIGAROLA, STEVEN SCOTT, SOFIA LOERA, BIXIN XI, TIMOTHY SYNOLD, SAMUEL RAHBAR

Journal:

Annals of the New York Academy of Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 3.74 MB

english, 2005

37

Dolastatin-10 in Metastatic Melanoma: A Phase II and Pharmokinetic Trial of the California Cancer Consortium

Kim Margolin, Jeffrey Longmate, Timothy W. Synold, David R. Gandara, Jeffrey Weber, Rene Gonzalez, Mary J. Johansen, Robert Newman, Tracey Baratta, James H. Doroshow

Journal:

Investigational New Drugs

Année:

2001

Langue:

english

Fichier:

PDF, 72 KB

english, 2001

38

High-dose paclitaxel in combination with doxorubicin, cyclophosphamide and peripheral blood progenitor cell rescue in patients with high-risk primary and responding metastatic breast carcinoma: toxicity profile, relationship to paclitaxel pharmacokinetics and short-term outcome

Somlo, G, Doroshow, J H, Synold, T, Longmate, J, Reardon, D, Chow, W, Forman, S J, Leong, L A, Margolin, K A, Jr, R J Morgan

Journal:

British Journal of Cancer

Année:

2001

Langue:

english

Fichier:

PDF, 95 KB

english, 2001

39

Validation of a Limited Sampling Model to Determine Etoposide Area Under the Curve

Bert L. Lum, Kevin J. Lane, Timothy W. Synold, Adrian Goram, Steven B. Charnick, Branimir I. Sikic

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Année:

1997

Langue:

english

Fichier:

PDF, 381 KB

english, 1997

40

Assessment of patient satisfaction utilizing the American Pain Society's quality assurance standards on acute and cancer-related pain

Christine Miaskowski, Rhonda Nichols, Robert Brody, Tim Synold

Journal:

Journal of Pain and Symptom Management

Année:

1994

Langue:

english

Fichier:

PDF, 905 KB

english, 1994

41

Pharmacology of oxaliplatin in solid tumor patients with hepatic dysfunction: a preliminary report of the national cancer institute organ dysfunction working group

James H Doroshow, Timothy W Synold, David Gandara, Sridhar Mani, Scot C Remick, Daniel Mulkerin, Anne Hamilton, Sunil Sharma, Ramesh K Ramanathan, Heinz Josef Lenz, Martin Graham, Jeffrey Longmate, Ch

Journal:

Seminars in Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 114 KB

english, 2003

42

Lack of Effect of P-glycoprotein Inhibition on Renal Clearance of Dicloxacillin in Patients with Cystic Fibrosis

Dr. Paul M. Beringer, Dr. Jane Kriengkauykiat, Ms. Xiyun Zhang, Dr. Levita Hidayat, Dr. Shanshan Liu, Dr. Stan Louie, Dr. Tim Synold, Dr. Gilbert J. Burckart, Dr. Purush A. Rao, Dr. Bertrand Shapiro,

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 101 KB

english, 2008

43

Southwest Oncology Group Phase II Study of Ispinesib in Androgen-Independent Prostate Cancer Previously Treated with Taxanes

Tomasz M. Beer, Bryan Goldman, Timothy W. Synold, Christopher W. Ryan, Lakshmi S. Vasist, Peter J. Van Veldhuizen Jr, Shaker R. Dakhil, Primo N. Lara Jr, Anibal Drelichman, Maha H.A. Hussain, E. David

Journal:

Clinical Genitourinary Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2008

44

Low transplant-related mortality after stem cell transplantation with IV busulfan-based conditioning in pediatric patients

E. Bolotin, L. Cooper, T. Synold, R. Sweetman, J. Mao, J. Palmer, J. Rosenthal

Journal:

Biology of Blood and Marrow Transplantation

Année:

2005

Langue:

english

Fichier:

PDF, 51 KB

english, 2005

45

Phase 2 study of targeted intravenous busulfan (IV BU) combined with fractionated total body irradiation (FTBI) and etoposide (VP-16) as preparative regimen for allogeneic peripheral blood stem cell transplant (PBSCT) for patients with poor risk leukemia

A.S. Stein, M.R. O’Donnell, A. Dagis, A. Krishnan, A. Nademanee, R. Nakamura, P.M. Parker, L. Popplewell, V. Pullarkat, R. Rodriguez, J. Rosenthal, E.P. Smith, D.S. Snyder, R. Spielberger, T. Synold,

Journal:

Biology of Blood and Marrow Transplantation

Année:

2006

Langue:

english

Fichier:

PDF, 58 KB

english, 2006

46

A study of radiotherapy modalities combined with continuous 5-FU infusion for locally advanced gastrointestinal malignancies

S.I Shibata, R Pezner, D Chu, J.H Doroshow, W.A Chow, L.A Leong, K.A Margolin, M.V McNamara, R.J Morgan Jr, J.W Raschko, G Somlo, M.L Tetef, Y Yen, T.W Synold, L Wagman, N Vora, M Carroll, S Lin, J Lo

Journal:

European Journal of Surgical Oncology (EJSO)

Année:

2004

Langue:

english

Fichier:

PDF, 129 KB

english, 2004

47

Methodologic guidelines for the design of high-dose chemotherapy regimens

Kim Margolin, Tim Synold, Jeff Longmate, James H. Doroshow

Journal:

Biology of Blood and Marrow Transplantation

Année:

2001

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2001

48

423 Phase 1 dose escalation, safety and pharmacokinetic study of IT-101 (CRLX101), a novel nanopharmaceutical containing camptothecin, in advanced solid tumor cancer patients

Y. Yen, T. Synold, G.J. Weiss, T. Schluep, J. Ryan

Journal:

European Journal of Cancer Supplements

Année:

2010

Langue:

english

Fichier:

PDF, 82 KB

english, 2010

49

661 A pharmacokinetic, pharmacodynamic and electrocardiographic study of L-MTP-PE in healthy volunteers

K. Venkatakrishnan, W.G. Kramer, T. Synold, D.B. Goodman, C. Oliva

Journal:

European Journal of Cancer Supplements

Année:

2010

Langue:

english

Fichier:

PDF, 99 KB

english, 2010

50

Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts

Doroshow, James H., Gaur, Shikha, Markel, Susan, Lu, Jiamo, van Balgooy, Josephus, Synold, Timothy W., Xi, Bixin, Wu, Xiwei, Juhasz, Agnes

Journal:

Free Radical Biology and Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2013